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4-Chloro-7-hydroxyquinazoline, a heterocyclic compound with the molecular formula C8H5ClN2O, belongs to the quinazoline class. It is a valuable intermediate in organic synthesis and medicinal chemistry, particularly for the development of pharmaceutical compounds such as anti-cancer and anti-inflammatory drugs. Its unique structure and reactivity contribute to its versatility in the production of biologically active molecules, making it a promising candidate for applications in the pharmaceutical and chemical industries.

849345-42-2

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849345-42-2 Usage

Uses

Used in Pharmaceutical Industry:
4-Chloro-7-hydroxyquinazoline is used as a building block for the synthesis of various pharmaceutical compounds, particularly for the development of anti-cancer and anti-inflammatory drugs. Its unique structure and reactivity enable the production of a range of biologically active molecules, contributing to the discovery and creation of novel therapeutic agents.
Used in Organic Synthesis:
4-Chloro-7-hydroxyquinazoline is used as a versatile intermediate in organic synthesis, allowing for the formation of complex molecular structures and the development of new chemical entities. Its reactivity and compatibility with various synthetic routes make it a valuable component in the synthesis of a wide array of compounds, expanding the scope of chemical research and innovation.
Used in Medicinal Chemistry:
4-Chloro-7-hydroxyquinazoline is employed as a key intermediate in medicinal chemistry, facilitating the design and synthesis of new drug candidates with potential therapeutic applications. Its unique structural features and reactivity enable the exploration of novel chemical space and the optimization of drug-like properties, ultimately contributing to the advancement of drug discovery efforts.

Check Digit Verification of cas no

The CAS Registry Mumber 849345-42-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,9,3,4 and 5 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 849345-42:
(8*8)+(7*4)+(6*9)+(5*3)+(4*4)+(3*5)+(2*4)+(1*2)=202
202 % 10 = 2
So 849345-42-2 is a valid CAS Registry Number.

849345-42-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-chloro-3H-quinazolin-7-one

1.2 Other means of identification

Product number -
Other names 4-chloroquinazoline-7-ol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:849345-42-2 SDS

849345-42-2Relevant academic research and scientific papers

QUINAZOLINE DERIVATIVES

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Page/Page column 120, (2008/06/13)

The invention concerns a quinazoline derivative of the Formula (I): wherein each of the variables have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an antiproliferative agent in the prevention or treatment of tumours which are sensitive to inhibition of erbB receptor tyrosine kinases.

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