Cas 849346-16-3,L-Proline, 4-[[4-[(3-chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1- methyl-, methyl ester, (4S)-

849346-16-3

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Basic information

Product Name: L-Proline, 4-[[4-[(3-chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1- methyl-, methyl ester, (4S)-
Synonyms:
CAS NO:849346-16-3
Molecular Formula: C22H22ClFN4O4
Molecular Weight: 460.892
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: L-Proline, 4-[[4-[(3-chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1- methyl-, methyl ester, (4S)-(CAS DataBase Reference)
NIST Chemistry Reference: L-Proline, 4-[[4-[(3-chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1- methyl-, methyl ester, (4S)-(849346-16-3)
EPA Substance Registry System: L-Proline, 4-[[4-[(3-chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1- methyl-, methyl ester, (4S)-(849346-16-3)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 849346-16-3(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 849346-16-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,9,3,4 and 6 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 849346-16:
(8*8)+(7*4)+(6*9)+(5*3)+(4*4)+(3*6)+(2*1)+(1*6)=203
203 % 10 = 3
So 849346-16-3 is a valid CAS Registry Number.

849346-16-3Upstream product

50-00-0 formaldehyd

849346-16-3Downstream Products

849346-17-4 (4S)-4-({4-[(3-chloro-2-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)-1-methyl-L-proline

849346-16-3Relevant academic research and scientific papers

QUINAZOLINE DERIVATIVES

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Page/Page column 160-162, (2008/06/13)

The invention concerns a quinazoline derivative of the Formula (I): wherein each of the variables have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an antiproliferative agent in the prevention or treatment of tumours which are sensitive to inhibition of erbB receptor tyrosine kinases.

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