849363-89-9Relevant academic research and scientific papers
Access to the new isoindolo[1,3]benzothiazocinones via the combination of N-acyliminium chemistry and friedel-crafts type π-cyclization
Cul, Armelle,Daich, Adam,Decroix, Bernard,Sanz, Gerard,Van Hijfte, Luc
, p. 33 - 39 (2007/10/03)
New racemic and chiral [4,2]- and [3,5]benzothiazocines (4) and (5) in the isoindolinone series were synthesized easily in few steps based on the combination of N-acyliminium chemistry and π-cationic cyclization of acylium ions. The chemoselectivity observed during these processes, particularly in the reduction, the thioalkylation and the cyclization stages, were also discussed.
