849367-75-5Relevant academic research and scientific papers
Synthesis of affinity nanoparticles coupled to FR901464 derivatives
Imamura, Yoshimasa,Ohtsu, Yoshihiro,Tanaka, Hiroshi,Hatakeyama, Mamoru,Manabe, Takashi,Kawaguchi, Haruma,Handa, Hiroshi,Takahashi, Takashi
, p. 51 - 56 (2007/10/03)
The synthesis of two latex nano-particles coupled to FR901464 derivatives is described. Two FR901464 derivatives attached with an amino-alkyl group at a different position were prepared from natural occurring FR 901464. Biological activities of the two ligands were significantly different. The acylation of two amino ligands with the activated esters on latex particles smoothly proceeded to provide the corresponding latex nano-particles coupled to FR 901464 at a different position.
