84938-06-7Relevant academic research and scientific papers
REACTIONS OF 1-(4,6-DIMETHOXYBENZOFURAN-5-YL) AND 1-(4,6,7-TRIMETHOXYBENZOFURAN-5-YL)BUTANE-1,2,3-TRIONE 2-ARYLHYDRAZONES WITH GRIGNARD REAGENTS
Zohair, Madiha M. Y.,Soliman, Fekria M. A.,Ahmed, Farid E.
, p. 1007 - 1014 (2007/10/02)
The reaction of 1-(4,6-dimethoxybenzofuran-5-yl) (1a-e) and 1-(4,6,7-trimethoxybenzofuran-5-yl)butane-1,2,3-trione 2-arylhydrazones (1f-i) with phenylmagnesium bromide, p-tolylmagnesium bromide or benzylmagnesium chloride involves a 1,2-addition of one mole of the Grignarg reagent with formation of hydroxyketones (2a-t) together with demethylation of the methoxy group at C-4.From hydroxyketones hydrazones (5a-p) were formed.Structure assignements for the new products were based upon analytical and spectral data.
