849402-27-3Relevant academic research and scientific papers
Comparative molecular field analysis and synthetic validation of a hydroxyamide-propofol binding and functional block of neuronal voltage-dependent sodium channels
Brown, Milton L.,Eidam, Hilary A.,Paige, Mikell,Jones, Paulianda J.,Patel, Manoj K.
experimental part, p. 7056 - 7063 (2009/12/24)
Voltage gated sodium channels represent an important therapeutic target for a number of neurological disorders including epilepsy. Unfortunately, medicinal chemistry strategies for discovering new classes of antagonist for trans-membrane ion channels have
Discovery of novel soluble crystalline anesthetics
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Page/Page column 9, (2010/11/25)
The invention discloses compounds derived from propofal which have greater aqueous solubility than propofal and are useful as anesthetic agents. The invention further discloses methods of preparing compounds of the invention. The invention also discloses
