Cas 849409-78-5,benzyl 4-[({(2S)-2-[(tert-butoxycarbonyl)amino]propanoyl}amino)methyl]benzoate

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Check Digit Verification of cas no

The CAS Registry Mumber 849409-78-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,9,4,0 and 9 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 849409-78:
(8*8)+(7*4)+(6*9)+(5*4)+(4*0)+(3*9)+(2*7)+(1*8)=215
215 % 10 = 5
So 849409-78-5 is a valid CAS Registry Number.

849409-78-5Upstream product

15761-38-3 L-N-Boc-Ala

849409-78-5Downstream Products

849409-79-6 benzyl 4-[(4S,7R,9S)-9-((1S)-1-{[3-(1,1-dioxo-1,6-isothiazolidin-2-yl)benzoyl]amino}-3-methylbutyl)-4,7,11,11,12,12-hexamethyl-3,6-dioxo-10-oxa-2,5-diaza-11-silatridec-1-yl]benzoate

849409-78-5Relevant academic research and scientific papers

NOVEL SULFONE AMIDE DERIVATIVES CAPABLE OF INHIBITING BACE

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Page/Page column 41-42, (2010/02/11)

The present invention relates to novel derivatives of sulfone amide of Formula 1 as defined in this disclosure which inhibit the activity of BACE (or beta-secretase). These sulfone amide derivatives are useful for the treatment and prevention of Alzheimer's disease and related diseases caused by production of beta-amyloid, by inhibiting the activity of BACE.

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