849442-46-2Relevant academic research and scientific papers
Discovery and SAR of para-alkylthiophenoxyacetic acids as potent and selective PPARδ agonists
Zhang, Rui,DeAngelis, Alan,Wang, Aihua,Sieber-McMaster, Ellen,Li, Xun,Russell, Ronald,Pelton, Patricia,Xu, Jun,Zhu, Peifang,Zhou, Lubing,Demarest, Keith,Murray, William V.,Kuo, Gee-Hong
scheme or table, p. 1101 - 1104 (2009/08/07)
Synthesis and SAR of para-alkylthiophenoxyacetic acids is described. Achiral compounds 30, 31 and 32 were identified as potent and selective PPARδ agonists.
4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS
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Page/Page column 71; 73, (2008/06/13)
The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia.
