849517-56-2Relevant academic research and scientific papers
New method for the synthesis of functionalized 1,3-bis-exocyclic dienes via a palladium-catalyzed reaction. Scope and synthetic applications
Lomberget, Thierry,Bouyssi, Didier,Balme, Genevieve
, p. 311 - 329 (2007/10/03)
The palladium-catalyzed tandem cyclization-coupling reaction of conjugated enynes having a stabilizing carbon nucleophile with aryl iodides and vinyl halides or triflates produced stereo-defined, functionalized five- and six-membered 1,3-bis-exocyclic dienes in moderate to good yields. These stereodefined dienes proved to be versatile substrates for the preparation of various polycyclic products through subsequent Diels-Alder, intramolecular Friedel-Crafts or thermal electrocyclization reactions.
