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3-Isoquinolinecarbonitrile, 1-chloro-4-(3-fluorophenyl)-6-methoxy- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

849546-48-1

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849546-48-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 849546-48-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,9,5,4 and 6 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 849546-48:
(8*8)+(7*4)+(6*9)+(5*5)+(4*4)+(3*6)+(2*4)+(1*8)=221
221 % 10 = 1
So 849546-48-1 is a valid CAS Registry Number.

849546-48-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-chloro-4-(3-fluorophenyl)-6-methoxyisoquinoline-3-carbonitrile

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:849546-48-1 SDS

849546-48-1Relevant academic research and scientific papers

Design and synthesis of novel isoquinoline-3-nitriles as orally bioavailable Kv1.5 antagonists for the treatment of atrial fibrillation

Trotter, B. Wesley,Nanda, Kausik K.,Kett, Nathan R.,Regan, Christopher P.,Lynch, Joseph J.,Stump, Gary L.,Kiss, Laszlo,Wang, Jixin,Spencer, Robert H.,Kane, Stefanie A.,White, Rebecca B.,Zhang, Rena,Anderson, Kenneth D.,Liverton, Nigel J.,McIntyre, Charles J.,Beshore, Douglas C.,Hartman, George D.,Dinsmore, Christopher J.

, p. 6954 - 6957 (2007/10/03)

Novel 3-cyanoisoquinoline Kv1.5 antagonists have been prepared and evaluated in in vitro and in vivo assays for inhibition of the Kv1.5 potassium channel and its associated cardiac potassium current, IKur. Structural modifications of isoquinoli

ISOQUINOLINE POTASSIUM CHANNEL INHIBITORS

-

Page/Page column 51, (2008/06/13)

The present invention relates to compounds having the structure (I) useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like.

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