849547-30-4 Usage
Chemical class
Isoquinolinecarboxylic acids
Molecular structure
Consists of an isoquinoline ring with various substituents
Substituents
Carboxylic acid group at position 1, cyano group at position 3, methoxy group at position 6, and phenyl group at position 4
Potential pharmacological activities
May have therapeutic effects
Synthesis applications
Can be used to create various drugs and pharmaceutical intermediates
Research and development potential
Unique molecular structure makes it suitable for further study in medicinal chemistry and drug discovery
Check Digit Verification of cas no
The CAS Registry Mumber 849547-30-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,9,5,4 and 7 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 849547-30:
(8*8)+(7*4)+(6*9)+(5*5)+(4*4)+(3*7)+(2*3)+(1*0)=214
214 % 10 = 4
So 849547-30-4 is a valid CAS Registry Number.
849547-30-4Relevant academic research and scientific papers
Design and synthesis of novel isoquinoline-3-nitriles as orally bioavailable Kv1.5 antagonists for the treatment of atrial fibrillation
Trotter, B. Wesley,Nanda, Kausik K.,Kett, Nathan R.,Regan, Christopher P.,Lynch, Joseph J.,Stump, Gary L.,Kiss, Laszlo,Wang, Jixin,Spencer, Robert H.,Kane, Stefanie A.,White, Rebecca B.,Zhang, Rena,Anderson, Kenneth D.,Liverton, Nigel J.,McIntyre, Charles J.,Beshore, Douglas C.,Hartman, George D.,Dinsmore, Christopher J.
, p. 6954 - 6957 (2007/10/03)
Novel 3-cyanoisoquinoline Kv1.5 antagonists have been prepared and evaluated in in vitro and in vivo assays for inhibition of the Kv1.5 potassium channel and its associated cardiac potassium current, IKur. Structural modifications of isoquinoli
ISOQUINOLINE POTASSIUM CHANNEL INHIBITORS
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, (2008/06/13)
The present invention relates to compounds having the structure (I) useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like.
