849547-86-0 Usage
Uses
Used in Pharmaceutical Synthesis:
3-Ethoxycarbonylmethyl-piperazine-1-carboxylic acid tert-buty酯 is used as an intermediate in the production of various drugs. Its unique chemical structure allows it to be a key component in the synthesis of a range of pharmaceuticals, contributing to the development of new medications.
Used in Agrochemical Production:
In the agrochemical industry, 3-ETHOXYCARBONYLMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER serves as an intermediate, playing a crucial role in the synthesis of various agrochemicals. Its application helps in the development of products designed to protect crops and enhance agricultural productivity.
Used as a Reagent in Organic Synthesis:
Beyond its applications in pharmaceuticals and agrochemicals, 3-Ethoxycarbonylmethyl-piperazine-1-carboxylic acid tert-butyl ester can also be utilized as a reagent in organic synthesis. Its versatility in chemical reactions makes it a valuable tool for researchers and chemists working on the development of new organic compounds.
Used in Medicinal Chemistry and Drug Development:
Due to its piperazine ring structure, which is prevalent in numerous bioactive molecules, 3-Ethoxycarbonylmethyl-piperazine-1-carboxylic acid tert-butyl ester may have potential applications in medicinal chemistry. It could be instrumental in the discovery and development of new drugs, particularly those targeting specific biological pathways or receptors.
Check Digit Verification of cas no
The CAS Registry Mumber 849547-86-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,9,5,4 and 7 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 849547-86:
(8*8)+(7*4)+(6*9)+(5*5)+(4*4)+(3*7)+(2*8)+(1*6)=230
230 % 10 = 0
So 849547-86-0 is a valid CAS Registry Number.
849547-86-0Relevant academic research and scientific papers
Malancona, Savina,Altamura, Sergio,Filocamo, Gessica,Kinzel, Olaf,Hernando, Jose Ignacio Martin,Rowley, Michael,Scarpelli, Rita,Steinkuehler, Christian,Jones, Philip
, p. 4422 - 4428 (2011)
The Hedgehog (Hh-) signaling pathway is a key developmental pathway which controls patterning, growth and cell migration in most tissues, but evidence has accumulated showing that many human tumors aberrantly reactivate this pathway. Smoothened antagonists offer opportunities for the treatment of malignancies dependent on the Hh pathway, and the most advanced clinical candidates are demonstrating encourage initial results. A novel series of [6,5]-bicyclic tetrahydroimidazo[1,5-a]pyrazine-1,3(2H,5H)-dione smoothened antagonists has been identified, and the series has been extensively explored to ascertain the key detriments for activity, demonstrating that the trans-2-phenylcyclopropyl and hydantoin ring systems are critical for potency, while a variety of urea substituents can be tolerated. The combination of these optimal groups gives smoothened antagonists with activity in the low nanomolar range.
