849599-77-5

Upstream product

• 2389-60-8 Z-Lys(Boc)-OH 
• 625386-12-1 5-amino-2-(p-methoxybenzyl)-2H-pyrazole-3-carboxylic acid methyl ester 
• 625386-10-9 2-(4-methoxybenzyl)-5-nitro-2H-pyrazole-3-carboxylic acid methyl ester 

Downstream Products

• 849599-81-1 C₅₄H₇₈N₁₀O₁₅ 
• 849599-80-0 N^ε-(tert-butyloxycarbonyl)-(S)-lysinyl-N^ε-(tert-butyloxycarbonyl)-(S)-lysinyl-5-amino-2-(4-methoxybenzyl)-2H-pyrazole-3-carboxylic acid methyl ester 
• 940963-91-7 5-{5-[2-[2-(2-methoxy-ethoxy)-ethoxy]-acetylamino]-2-(4-methoxybenzyl)-2H-pyrazole-3-cabonyl-(S)-phenylalanyl-N⁶-tert-butyloxycarbonyl-(S)-lysyl-amino}-2-(4-methoxybenzyl)-2H-pyrazole-3-carboxylic acid methyl ester 
• 940963-90-6 5-{5-[2-[2-(2-methoxy-ethoxy)-ethoxy]-acetylamino]-2-(4-methoxybenzyl)-2H-pyrazole-3-cabonyl-(S)-alanyl-N⁶-tert-butyloxycarbonyl-(S)-lysyl-amino}-2-(4-methoxybenzyl)-2H-pyrazole-3-carboxylic acid methyl ester 
• 940963-87-1 5-((S)-phenylalanyl-N⁶-tert-butyloxycarbonyl-(S)-lysyl-amino)-2-(4-methoxybenzyl)-2H-pyrazole-3-carboxylic acid methyl ester 
• 940963-86-0 5-((S)-alanyl-N⁶-tert-butyloxycarbonyl-(S)-lysyl-amino)-2-(4-methoxybenzyl)-2H-pyrazole-3-carboxylic acid methyl ester 
• 940963-83-7 5-(N-benzyloxycarbonyl-(S)-phenylalanyl-N⁶-tert-butyloxycarbonyl-(S)-lysyl-amino)-2-(4-methoxybenzyl)-2H-pyrazole-3-carboxylic acid methyl ester 
• 940963-82-6 5-(N-benzyloxycarbonyl-(S)-alanyl-N⁶-tert-butyloxycarbonyl-(S)-lysyl-amino)-2-(4-methoxybenzyl)-2H-pyrazole-3-carboxylic acid methyl ester 
• 849599-79-7 N^ε-(tert-butyloxycarbonyl)-(S)-lysinyl-5-amino-2-(4-methoxybenzyl)-2H-pyrazole-3-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Synthesis and binding studies of Alzheimer ligands on solid support

(Chemical Equation Presented) Aminopyrazole derivatives constitute the first class of nonpeptidic rationally designed β-sheet ligands. Here we describe a double solid-phase protocol for both synthesis and affinity testing. The presented solid-phase synthe

β-sheet ligands in action: KLVFF recognition by aminopyrazole hybrid receptors in water

Little is known about the precise mechanism of action of β-sheet ligands, hampered by the notorious solubility problems involved with protein misfolding and amyloid formation. Recently the nucleation site for the pathogenic aggregation of the Alzheimer's