84962-44-7

Usage

InChI:InChI=1/C13H20O3/c1-3-4-5-6-10-11(14)7-8-13(10,2)9-12(15)16/h6H,3-5,7-9H2,1-2H3,(H,15,16)/p-1/b10-6-

Upstream product

• 878564-27-3 2-butyl-1,5,8-trioxadispiro[2.0.4.3]undecane 
• 878564-30-8 1-(1,4-dioxaspiro[4.4]non-6-en-6-yl)pentan-1-ol 
• 930-30-3 cyclopent-2-enone 
• 110-62-3 pentanal 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 67382-39-2 2-(E)-pentylidene cyclopentanone 
• 878564-23-9 (6E)-6-pentylidene-1,4-dioxaspiro[4.4]nonane 
• 694528-26-2 2-(1-hydroxypentyl)cyclopent-2-en-1-one 
• 1445-45-0 Trimethyl orthoacetate 

Relevant academic research and scientific papers

New compounds having PPAR-γ activity, and medical use thereof

The present invention relates to a novel compound having PPAR-andgamma; activity and to a medical use thereof. According to the present invention, an exocyclic enone jasmonate derivative acting as a PPAR-andgamma; activator is synthesized by binding an an

Rh-catalyzed highly enantioselective formation of functionalized cyclopentanes and cyclopentanones

A catalyst system, [Rh(COD)Cl]2-BINAP-AgSbF6, has been developed as a second-generation catalyst for the cycloisomerization of 1,6-enynes tethered by carbon chains. Cyclopentanes and cyclopentanones, which can contain functional grou

2-ALKYLIDENE- AND 2-(ALKYL-1-ENE)-CYCLOPENTANONE AS PERFUMES

The invention relates to the use of a compound of formula (Ia) or (Ib) as a jasmine perfume. In each of the formulae (Ia) and (Ib), R1 represents H or methyl and R2 represents a branched or unbranched C1 to C5 alkyl group.

Synthesis of cis-Hedione and methyl jasmonate via cascade Baylis-Hillman reaction and Claisen ortho ester rearrangement

The exocyclically unsaturated conjugated keto esters 10, obtained via a Claisen ortho ester rearrangement of the allylic hydroxy ketones 9, were either directly hydrogenated or partially isomerized into the endocyclically unsaturated tetrasubstituted didehydrojasmonoid intermediates 14, prior to a more selective hydrogenation with Pd/C in cyclohexane to the disubstituted oxocyclopentaneacetates 15 (Scheme 2). The key intermediates 9 were obtained either by a four-step sequence, including acetal protection/deprotection from enone 1, in the specific case of hydroxy ketone 9a (Scheme 1), or more directly and generally by a Baylis-Hillman reaction from cyclopent-2-en-1-one (16) and the appropriate aldehydes 17 (Scheme 2). The judicious choice of these aldehydes opens versatile modifications for the stereoselective introduction of the partially cis- or epimerized trans-C(2) jasmonoid side chain, while the Baylis-Hillman reaction, catalyzed by chiral [1,1′-binaphthalene]-2, 2′-diols (BINOLs) 19 (Scheme 3), may be efficiently conducted in a one-pot cascade fashion including the ortho ester Claisen rearrangement.

A PROCESS FOR THE PREPARATION OF ALKYLIDENECYCLOPENTANONE DERIVATIVES

The present invention relates to the field of organic synthesis and more particularly to a new process for the preparation of a compound of formula (I), in the form of any one of its isomers or a mixture thereof, Formula (I) wherein, more preferably, G represents a C=O group, R1 represents a butyl group and R2 represents a methyl group. The process of the invention involves an 2-(1-hydroxyalkyl)-cyclopent-2-en-1-one derivative, as starting material, which can be then converted into a compound of formula (I) by a process comprising a thermal rearrangement. The 2-alkylidene-3-oxo-cyclopentylacetate derivative and the 2-(1-hydroxyalkyl)-cyclopent-2-en-1-one derivative are also an object of the invention.