849752-43-8

Upstream product

• 170943-16-5 methyl (((9H-fluoren-9-yl)methoxy)carbonyl)-L-lysinate 
• 172846-56-9 methyl N²-(((9H-fluoren-9-yl)methoxy)carbonyl)-N⁶-(tert-butoxycarbonyl)-L-lysinate 
• 71989-26-9 Fmoc-Lys(tert-butoxycarbonyl) 
• 849752-40-5 2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[2-(4-trifluoromethyl-benzenesulfonyl)-ethoxycarbonylamino]-hexanoic acid methyl ester 
• 105047-45-8 Fmoc-Lys-OH 

Relevant academic research and scientific papers

Orthogonality and compatibility between Tsc and Fmoc amino-protecting groups

New deprotection conditions that provide a complete orthogonality between Tsc and Fmoc amino-protecting groups are described. The potential of these orthogonal deprotection conditions was then demonstrated by the efficient solid-phase synthesis of branched peptides 20 and 21 using doubly protected amino acids such as Tsc-Lys(Fmoc)-OH 4c and Fmoc-Lys(Tsc)-OH 4d.