849752-69-8Relevant academic research and scientific papers
Entry into a new class of potent proteasome inhibitors having high antiproliferative activity by structure-based design
Furet, Pascal,Imbach, Patricia,Noorani, Maria,Koeppler, Juergen,Laumen, Kurt,Lang, Marc,Guagnano, Vito,Fuerst, Peter,Roesel, Johannes,Zimmermann, Johann,García-Echeverría, Carlos
, p. 4810 - 4813 (2004)
Proteasome inhibition is a therapeutic concept of current interest in anticancer research. We report here the design, synthesis, and biological characterization of prototypes of a new class of noncovalent proteasome inhibitors showing high activity in bio
