849801-80-5Relevant academic research and scientific papers
Microwave-assisted one-pot synthesis of antifungal active l-substituted-3, 7- Dialkyl/aryl-4H-pyrazolo[4, 5-f]- [l, 2, 4]triazolo[3, 4-6][l, 3, 4]thiadiazepines using solid support
Gupta, Monika,Paul, Satya,Gupta, Rajive
scheme or table, p. 460 - 466 (2009/12/26)
A simple, efficient and environment-friendly procedure is developed for the synthesis of l-substitued-3, 7-diaikyl/aryl-4H-pyrazolo[4, 5-f][l, 2, 4]triazolo[3, 4-6][l, 3, 4]thiadiazepines 3 by condensation of l-amino-2-mercapto-l, 3, 4-triazoles 1 and 5-chloro-4-formyl-l, 2-pyrazoles 2 in the presence of N,N-dimethyl-formamide as an energy transfer medium, p-TsOH as catalyst and basic alumina as solid support under microwave irradiation. The products are obtained in good to moderate yields and are in a state of high purity.
