849807-01-8 Usage
Description
4-[(2-fluorophenyl)methoxy]phenylmethanamine is a complex chemical compound derived from methanamine. It features a central methanamine group connected to a phenyl ring, which is further attached to another phenyl ring with a methoxy group and a fluorophenyl group. 4-[(2-fluorophenyl)methoxy]phenylmethanamine is utilized in pharmaceutical research and development, and it may hold potential applications in treating various diseases and conditions, as well as in the synthesis of other chemical compounds. Further research and testing are required to determine its specific properties and potential uses.
Uses
Used in Pharmaceutical Research and Development:
4-[(2-fluorophenyl)methoxy]phenylmethanamine is used as a chemical intermediate for the development of new pharmaceutical compounds. Its unique molecular structure may contribute to the creation of novel drugs with potential applications in treating various diseases and conditions.
Used in Synthesis of Other Chemical Compounds:
4-[(2-fluorophenyl)methoxy]phenylmethanamine serves as a building block in the synthesis of other complex chemical compounds, which could have a wide range of applications in different industries, including pharmaceuticals, materials science, and chemical manufacturing.
Used in Treatment of Various Diseases and Conditions:
Although further research is needed, 4-[(2-fluorophenyl)methoxy]phenylmethanamine may have potential applications in the treatment of various diseases and conditions due to its unique molecular structure and properties. It could be explored for its potential therapeutic effects in areas such as oncology, neurology, and cardiovascular medicine.
Check Digit Verification of cas no
The CAS Registry Mumber 849807-01-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,9,8,0 and 7 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 849807-01:
(8*8)+(7*4)+(6*9)+(5*8)+(4*0)+(3*7)+(2*0)+(1*1)=208
208 % 10 = 8
So 849807-01-8 is a valid CAS Registry Number.
849807-01-8Relevant articles and documents
Hitting on the move: Targeting intrinsically disordered protein states of the MDM2-p53 interaction
Neochoritis, Constantinos G.,Atmaj, Jack,Twarda-Clapa, Aleksandra,Surmiak, Ewa,Skalniak, Lukasz,K?hler, Lisa-Maria,Muszak, Damian,Kurpiewska, Katarzyna,Kalinowska-T?u?cik, Justyna,Beck, Barbara,Holak,D?mling, Alexander
supporting information, (2019/08/20)
Intrinsically disordered proteins are an emerging class of proteins without a folded structure and currently disorder-based drug targeting remains a challenge. p53 is the principal regulator of cell division and growth whereas MDM2 consists its main negative regulator. The MDM2-p53 recognition is a dynamic and multistage process that amongst other, employs the dissociation of a transient α-helical N-terminal ‘‘lid’’ segment of MDM2 from the proximity of the p53-complementary interface. Several small molecule inhibitors have been reported to inhibit the formation of the p53-MDM2 complex with the vast majority mimicking the p53 residues Phe19, Trp23 and Leu26. Recently, we have described the transit from the 3-point to 4-point pharmacophore model stabilizing this intrinsically disordered N-terminus by increasing the binding affinity by a factor of 3. Therefore, we performed a thorough SAR analysis, including chiral separation of key compound which was evaluated by FP and 2D NMR. Finally, p53-specific anti-cancer activity towards p53-wild-type cancer cells was observed for several representative compounds.
Benzyloxybenzylammonium chlorides: Simple amine salts that display anticonvulsant activity
Lee, Hyosung,Gold, Alexander S.,Yang, Xiao-Fang,Khanna, Rajesh,Kohn, Harold
, p. 7655 - 7662 (2014/01/06)
Several antiepileptic drugs exert their activities by inhibiting Na + currents. Recent studies demonstrated that compounds containing a biaryl-linked motif (Ar-X-Ar′) modulate Na+ currents. We, and others, have reported that compound
