84989-88-8

Upstream product

• 73593-64-3 3,3-Dimethyl-4-oxo-4-phenylbutansaeure-methylester 
• 344312-64-7 2-Methoxy-3,3-dimethyl-2-phenylcyclopropancarbonsaeure 

Downstream Products

• 84989-89-9 4,5-Dihydro-5-methoxy-4,4-dimethyl-5-phenyl-2(3H)-furanon 

Relevant academic research and scientific papers

METHOD FOR INHIBITING THE REPLICATION OF HERPES VIRUSES

The invention relates to a method for inhibiting the replication of herpes viruses, to methods for identifying compounds that inhibit the replication of herpes viruses with this method, to compounds with activity directed against herpes viruses, to methods for producing these compounds, and to the use thereof for producing medicaments used in the treatment of herpes infections.

Isomerisation of 2-Alkoxycyclopropanecarboxylic Acids - An Effective Synthesis of 4-Oxo Carboxylic Acids

(Z/E)-2-Alkoxycyclopropanecarboxylic esters 2/3 were prepared from enol ethers 1 and ethyl diazoacetate.The saponification of these esters gives the corresponding (Z/E)-2-alkoxycyclopropanecarboxylic acids 4/5, which show stereomutation in water/methanol.This isomerisation was studied in labelled solvents and interpreted for the example of (E)-2-methoxy-2-phenylcyclopropanecarboxylic acid (5a).On heating in water/methanol the compounds 4/5 are transformed quantitatively into the corresponding 4-oxo carboxylic acids 6.