84990-06-7

Basic information

• Product Name: ethyl 1,3-dimethyl-4-oxo-5-(piperidin-1-ylmethylidene)-4,5,6,7-tetrahydro-1H-indole-2-carboxylate
• CAS NO: 84990-06-7
• Molecular Formula: C₁₉H₂₆N₂O₃
• Molecular Weight: 330.4213
• Mol File: 84990-06-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 510.7°C at 760 mmHg
• Flash Point: 262.6°C
• Density: 1.21g/cm³
• Vapor Pressure: 1.52E-10mmHg at 25°C
• Refractive Index: 1.596
• CAS DataBase Reference: ethyl 1,3-dimethyl-4-oxo-5-(piperidin-1-ylmethylidene)-4,5,6,7-tetrahydro-1H-indole-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 1,3-dimethyl-4-oxo-5-(piperidin-1-ylmethylidene)-4,5,6,7-tetrahydro-1H-indole-2-carboxylate(84990-06-7)
• EPA Substance Registry System: ethyl 1,3-dimethyl-4-oxo-5-(piperidin-1-ylmethylidene)-4,5,6,7-tetrahydro-1H-indole-2-carboxylate(84990-06-7)

Safety Data

• Hazardous Substances Data: 84990-06-7(Hazardous Substances Data)

Upstream product

• 110-89-4 piperidine 
• 54874-78-1 2-carbethoxy-5-hydroxymethylene-1,3-dimethyl-4-oxo-4,5,6,7-tetrahydroindole 

Relevant articles and documents

Synthesis of Heterocycles Using 4-Oxo-4,5,6,7-tetrahydroindoles as Biodynamic Molecules

Various heterocyclic compounds have been prepared using 4-oxo-4,5,6,7-tetrahydroindoles.Conversion of 2-carbethoxy-1,3-dimethyl- and 1,3-dimethyl-4-oxo-4,5,6,7-tetrahydroindoles (2 and 4) to 5-hydroxymethylene derivatives (5 and 6) followed by their treatment with hydroxylamine and hydrazine gives the corresponding isoxazoles (16-17) and pyrazoles (18-21) respectively.Reaction of 2 with diethyl carbonate furnishes the 5-carbethoxy derivative (27) which on treatment with guanidine affords the pyrimidine derivative (28).Bromination of 2 with triethylammonium perbromide and subsequent treatment of bromo compound (29) with thiourea gives the thiazole derivative (30).None of the compounds shows any noteworthy antibacterial, antifungal or antiamoebic activity.