849934-89-0

Basic information

• Product Name: 2-METHYLSULFANYL-5-(4,4,5,5-TETRAMETHYL-[1,3,2]-DIOXABOROLAN-2-YL)PYRIDINE
• Synonyms: 2-METHYLSULFANYL-5-(4,4,5,5-TETRAMETHYL-[1,3,2]-DIOXABOROLAN-2-YL)PYRIDINE;6-(METHYLSULFANYL)PYRIDINE-3-BORONIC ACID, PINACOL ESTER;6-(Methylthio)pyridine-3-boronic acid pinacol ester, 95%;2-Methylthio-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine;2-Methylthiopyridine-5-boronic acid, pinacol ester
• CAS NO: 849934-89-0
• Molecular Formula: C₁₂H₁₈BNO₂S
• Molecular Weight: 251.15282
• Mol File: 849934-89-0.mol
• Article Data: 5

Chemical Properties

• Melting Point: 165-168℃
• Boiling Point: 362.2°C at 760 mmHg
• Flash Point: 172.9°C
• Appearance: /
• Density: 1.1g/cm³
• Vapor Pressure: 4.1E-05mmHg at 25°C
• Refractive Index: 1.525
• CAS DataBase Reference: 2-METHYLSULFANYL-5-(4,4,5,5-TETRAMETHYL-[1,3,2]-DIOXABOROLAN-2-YL)PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYLSULFANYL-5-(4,4,5,5-TETRAMETHYL-[1,3,2]-DIOXABOROLAN-2-YL)PYRIDINE(849934-89-0)
• EPA Substance Registry System: 2-METHYLSULFANYL-5-(4,4,5,5-TETRAMETHYL-[1,3,2]-DIOXABOROLAN-2-YL)PYRIDINE(849934-89-0)

Safety Data

• Hazardous Substances Data: 849934-89-0(Hazardous Substances Data)

Usage

General Description

2-Methylsulfanyl-5-(4,4,5,5-tetramethyl-[1,3,2]-dioxaborolan-2-yl)pyridine is a specialized chemical compound that falls within the category of organosulfur compounds and organoboron compounds. 2-METHYLSULFANYL-5-(4,4,5,5-TETRAMETHYL-[1,3,2]-DIOXABOROLAN-2-YL)PYRIDINE carries a pyridine core, with additional functional groups like methylsulfanyl and tetramethyl dioxaborolane attached to it. Very often, it is used in the field of organic chemistry, especially in synthesis reactions involving boronic compounds, where it can react with other components to create a variety of different products. Its exact properties, such as melting point, boiling point, or solubility, can vary depending on the composition and purity of the batch, as well as the surrounding conditions.

InChI:InChI=1/C12H18BNO2S/c1-11(2)12(3,4)16-13(15-11)9-6-7-10(17-5)14-8-9/h6-8H,1-5H3

Upstream product

• 53939-30-3 5-bromo-2-chloropyridine 
• 51933-78-9 5-bromo-2-(methylsulfanyl)pyridine 
• 73183-34-3 bis(pinacol)diborane 
• 624-28-2 2,5-dibromopyridine 
• 123-91-1 1,4-dioxane 

Downstream Products

• 849934-68-5 1-(2,4-difluoro-benzyl)-6-[5-(6-methylsulfanyl-pyridin-3-yl)-thiophen-2-yl]-2-oxo-4-trifluoromethyl-1,2-dihydro-pyridine-3-carbonitrile 
• 1416000-41-3 2-(6-(methylthio)pyridin-3-yl)-10-(3-(trifluoromethyl)phenyl)pyrido[3,2-c][1,5]naphthyridin-9(10H)-one 

Relevant articles and documents

PYRAZOLOPYRIMIDINE DERIVATIVE AND USE THEREOF AS PI3K INHIBITOR

The present invention discloses a series of pyrazolopyrimidine derivatives and use thereof in preparing a medicament for treating a disease related to PI3K, and in particular, discloses a derivative compound of formula (I), a tautomer thereof or a pharmaceutically acceptable composition thereof.

Pyridonaphthyridine PI3K/MTOR Dual Inhibitors and Preparation and Use Thereof

The present invention relates to a pyridonaphthyridine compound as represented by general formula (I), which has a dual PI3K and mTOR inhibition effect, and its pharmaceutically acceptable salt, stereoisomer and deuteride thereof, wherein R1, R2, R3, R4, R5, R6, R7 and X are as defined in the specification; the present invention also relates to a method for preparing said compound, a pharmaceutical composition and a pharmaceutical formulation containing said compound, and uses of said compound in treating and/or preventing a proliferative disease and in the manufacture of a medicament for treating and/or preventing a proliferative disease.

Modulators of LXR

Compounds of the invention, such as compounds of formula (I): where n, m, A, B, R1, R2, R3, R4 and R5 are defined herein, are useful as modulators of the activity of liver X receptors. Pharmaceutical compositions containing the compounds and methods of using the compounds are also disclosed.