849934-90-3

Upstream product

• 112930-39-9 3-bromo-5-isopropylbenzoic acid 
• 62655-20-3 1,3-dibromo-5-isopropylbenzene 

Downstream Products

• 112930-40-2 t-butyl N-(3-bromo-5-isopropylphenyl)carbamate 
• 112930-24-2 1-(biphenyl-2'-yl)-1-(3-fluoro-5-isopropylphenyl)but-3-en-1-ol 
• 112930-20-8 α-(3'-fluoro-5'-isopropylphenyl)biphenyl-2-methanol 
• 112930-27-5 (E,Z)-1-(biphenyl-2'-yl)-1-(3-fluoro-5-isopropylphenyl)buta-1,3-diene 
• 112930-22-0 (biphenyl-2'-yl)(3-fluoro-5-isopropylphenyl)methanone 
• 112930-41-3 3-bromo-5-isopropylacetanilide 
• 112930-19-5 3-bromo-5-fluorocumene 
• 112930-36-6 3-bromo-5-isopropylaniline 

Relevant academic research and scientific papers

Modulators of LXR

Compounds of the invention, such as compounds of formula (I): where n, m, A, B, R1, R2, R3, R4 and R5 are defined herein, are useful as modulators of the activity of liver X receptors. Pharmaceutical compositions containing the compounds and methods of using the compounds are also disclosed.

Steric Effects. Internal Rotation of 1-Aryl-8-phenylnaphthalenes

A general, albeit low-yielding, synthesis of 1-aryl-8-phenylnaphthalenes was devised and used to prepare three 1-(3'-X-5'-isopropylphenyl)-8-phenylnaphthalenes (X = H, F, Br).Activation parameters for the rotation of the 3'-X-5'-isopropylphenyl group were