849943-87-9Relevant academic research and scientific papers
Preparation of enamides via palladium-catalyzed amidation of enol tosylates
Klapars, Artis,Campos, Kevin R.,Chen, Cheng-Yi,Volante, Ralph P.
, p. 1185 - 1188 (2005)
(Chemical Equation Presented) A Pd-catalyzed coupling of enol tosylates and amides has been developed. Ligand screening revealed dipf as the most general ligand for this transformation. A variety of enol tosylates were coupled to an array of enamides in 5
Nickel-Catalyzed Cyanation of Phenol Derivatives with Zn(CN)2 Involving C-O Bond Cleavage
Gan, Yi,Wang, Gaonan,Xie, Xin,Liu, Yuanhong
, p. 14036 - 14048 (2018/11/03)
An efficient nickel-catalyzed cyanation of aryl sulfonates, fluorosulfonates, and sulfamates with Zn(CN)2 was developed, which provides a facile access to the nitrile products in generally good to excellent yields. The reaction is accomplished by using NiII complex as the precatalyst and DMAP as the additive. The method also displays wide functional group compatibility; for example, keto, methoxy, N,N-dimethylamino, cyano, ester, and pyridyl groups are well-tolerated during the reaction process.
Preparation of α,β-unsaturated esters and amides via external-CO-free palladium-catalyzed carbonylation of alkenyl tosylates
Ueda, Tsuyoshi,Konishi, Hideyuki,Manabe, Kei
supporting information; experimental part, p. 5171 - 5175 (2012/09/25)
Palladium-catalyzed carbonylation of tosylates with phenyl formate is described. This procedure needs neither external carbon monoxide nor any pressure-resistant apparatus. A variety of cyclic and acyclic alkenyl tosylates can be converted into the corresponding phenyl esters in good yields. Furthermore, this method is effective for the one-pot synthesis of α,β-unsaturated amides.
