849950-08-9Relevant academic research and scientific papers
Syntheses and biological activities of rebeccamycin analogues with uncommon sugars
Zhang, Guisheng,Shen, Jie,Cheng, Hao,Zhu, Lizhi,Fang, Lanyan,Luo, Sanzhong,Muller, Mark T.,Lee, Gun Eui,Wei, Lijun,Du, Yuguo,Sun, Duxin,Wang, Peng George
, p. 2600 - 2611 (2007/10/03)
Rebeccamycin analogues containing uncommon sugars and substitutions on the imide nitrogen have been synthesized. Their cytotoxicities were tested in colon cancer and leukemia cells. Their ability to target topoisomerase I was examined using the in vivo co
