850133-65-2Relevant academic research and scientific papers
Synthesis of thiadiazoles, triazoles and oxadiazoles from sulfonyl acetic acids via a common route
Padmavathi, Venkatapuram,Thriveni, Pinnu,Reddy, Boggu Jagan Mohan,Padmaja, Adivireddy
, p. 113 - 116 (2005)
A new class of five membered heterocycles, thiadiazoles, triazoles and oxadiazoles were prepared from sulfonyl acetic acids via acid hydrazides.
Synthesis of Symmetrical Bis(5-substituted oxadiazolyl/thiadiazolyl/triazolylmethyl)sulfones
Adivireddy, Padmaja,Devanaboina, Pedamalakondaiah,Gopala, Lavanya,Chittoor, Rajasekhar
, p. 1651 - 1654 (2016/09/23)
A new class of bis(oxadiazolyl/thiadiazolyl/triazolylmethyl)sulfones were prepared by the cyclocondensation of sulfonyldiacetic acid with aryl acid hydrazide and arylmethanesulfonylacetic acid hydrazide.
Synthesis and antimicrobial activity of pyrazolyl 1,3,4-oxadiazoles
Padmavathi, Venkatapuram,Reddy, Gali Sudhakar,Reddy, Guda Dinneswara,Payani, Thalari
scheme or table, p. 482 - 493 (2010/04/06)
The pyrazolyl oxadiazoles are synthesized from arylsulfonylacetic acid methyl ester and benzylsulfonylacetic acid methyl ester. Preliminary antimicrobial screening of the compounds showed that bis heterocycles with a chloro-substituted benzyl moiety exhibited high activity. Copyright Taylor & Francis Group, LLC.
Synthesis, antimicrobial and cytotoxic activities of 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazoles
Padmavathi,Sudhakar Reddy,Padmaja,Kondaiah,Ali-Shazia
experimental part, p. 2106 - 2112 (2009/09/25)
A new class of 1,3,4-oxadiazoles were prepared from acid hydrazides on treatment with different carboxylic acids in the presence of phosphorus oxychloride. Interconversion of oxadiazoles to thiadiazoles and triazoles was carried out with appropriate reagents. The antimicrobial and cytotoxic activities of compounds 7a-d to 12a-d were tested. Compounds 10d and 12d showed pronounced antimicrobial activity. Further, compound 10d exhibited maximum cytotoxicity.
