850143-56-5 Usage
Chemical class
Oxadiazoles It belongs to a class of heterocyclic compounds with a five-membered ring containing oxygen and nitrogen atoms.
Structure
Heterocyclic compound The compound has a five-membered ring with oxygen and nitrogen atoms, making it a heterocyclic compound.
Phenyl group
Contains a phenyl group The compound has a phenyl group (C6H5) attached to it.
Substituent
Tetradecylthio The phenyl group has a tetradecylthio (C14H29S) substituent, which is a long-chain alkyl group with a sulfur atom.
Potential applications
Pharmaceuticals and agrochemicals Due to its structural features, the compound has potential applications in the fields of pharmaceuticals and agrochemicals.
Drug design
Suitability for drug design The compound's structure makes it a candidate for drug design, as it can be modified and optimized for specific therapeutic targets.
Agricultural applications
Potential for use in agrochemicals The compound's properties may also make it suitable for use in the development of new agrochemicals, such as pesticides or herbicides.
Research and development
Further exploration The compound's properties and potential uses can be further explored through research and development, which may lead to new applications and discoveries.
Molecular weight
Approximately 383.58 g/mol The molecular weight of the compound is calculated based on its chemical formula and the atomic weights of its constituent elements.
Check Digit Verification of cas no
The CAS Registry Mumber 850143-56-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,0,1,4 and 3 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 850143-56:
(8*8)+(7*5)+(6*0)+(5*1)+(4*4)+(3*3)+(2*5)+(1*6)=145
145 % 10 = 5
So 850143-56-5 is a valid CAS Registry Number.
850143-56-5Relevant academic research and scientific papers
Inhibition of secretory phospholipase A2. 2-Synthesis and structure-activity relationship studies of 4,5-dihydro-3-(4-tetradecyloxybenzyl) -1,2,4-4H-oxadiazol-5-one (PMS1062) derivatives specific for group II enzyme
Dong, Chang-Zhi,Ahamada-Himidi, Azali,Plocki, Stephanie,Aoun, Darina,Touaibia, Mohamed,Meddad-Bel Habich, Nadia,Huet, Jack,Redeuilh, Catherine,Ombetta, Jean-Edouard,Godfroid, Jean-Jacques,Massicot, France,Heymans, Francoise
, p. 1989 - 2007 (2007/10/03)
We have recently reported the discovery of a series of specific inhibitors of human group IIA phospholipase A2 (hGIIA PLA2) to display promising in vitro and in vivo properties. Here we describe the influence of different structural modifications on the specificity and potency against hGIIA PLA2 versus porcine group IB PLA2. The SAR results, as well as the log P and pKa values of oxadiazolone determined in this work, provide important information towards the comprehension of the mode of action of this kind of compounds.
