85019-65-4Relevant academic research and scientific papers
ENAMINE-ENAMINE ISOMERISM IN THE SERIES OF PRODUCTS FROM N-ACYLATION OF N-BENZYL-2-(β-CYANOETHYL)CYCLOHEXANIMINE
Erzhanov, K. B.,Kayukova, L. A.,Yakimovich, S. I.,Umarova, Z. N.,Krasnomolova, L. P.
, p. 2033 - 2036 (2007/10/02)
The equilibrium between the enamine forms with the trisubstituted and tetrasubstituted double bonds in the products from N-acylation of N-benzyl-2-(β-cyanoethyl)cyclohexanimine was investigated by PMR spectroscopy.The isomerization process is characterized by positive values for the changes in enthalpy and entropy.The two enamine forms exist in the chiral conformations, where the substituents at the nitrogen atom do not lie in the plane of the C=C bond.The free energy of activation for rotation about the Csp2-N bond in the enamine forms with trisubstituted and tetrasubstituted double bonds was determined.
REACTION OF 1-BENZYLIMINO-2-(β-CYANOETHYL)CYCLOHEXANE WITH CARBOXYLIC ACID CHLORIDES
Erzhanov, K. B.,Kayukova, L. A.,Umarova, Z. N.,Yakimovich, S. I.
, p. 2106 - 2111 (2007/10/02)
The acylation of 1-benzylimino-2-(β-cyanoethyl)cyclohexane with carboxylic acid chlorides is regiospecific and leads to the formation of N-acylation products.The latter exist as mixture of two enamine forms with trisubstituted and tetrasubstituted double
