850200-29-2Relevant academic research and scientific papers
Carbohydrate sulfonyl chlorides for simple, convenient access to glycoconjugates
Kvaerno, Lisbet,Werder, Moritz,Hauser, Helmut,Carreira, Erick M.
, p. 1145 - 1148 (2007/10/03)
(Chemical Equation Presented) The use of carbohydrate sulfonyl chlorides is introduced as a new, facile glycoconjugation method which could find broad applications. We demonstrate the approach by synthesizing a number of glycosylated cholesterol absorptio
Synthesis and in vitro evaluation of inhibitors of intestinal cholesterol absorption
Kv?rn?, Lisbet,Werder, Moritz,Hauser, Helmut,Carreira, Erick M.
, p. 6035 - 6053 (2007/10/03)
We have utilized our recently developed in vitro assay to address two key questions in the design of small-molecule cholesterol absorption inhibitors using ezetimibe, the only drug yet approved for the inhibition of cholesterol absorption in the small int
