85028-39-3Relevant academic research and scientific papers
Direct construction of a quaternary carbon center utilizing an organosamarium reagent
Li, Zhifang,Zhang, Yongmin
, p. 8507 - 8510 (2001)
Direct geminal diallylation of lactams and acyclic amides containing an N-H bond has been achieved in the presence of allylsamarium bromide. By applying this method, quaternary carbons have been constructed, and 2,2-diallylated nitrogen heterocycles and d
Dimethylzinc-Mediated Chlorolactamization of Homoallylic Amines with Chloroform
Nishida, Yuika,Ueda, Masafumi,Hayashi, Masataka,Takeda, Norihiko,Miyata, Okiko
supporting information, p. 22 - 25 (2016/01/26)
A novel chlorolactamization reaction of homoallylic amines has been developed. The treatment of homoallylic amines with dimethylzinc in chloroform led to the formation of the corresponding β-chlorolactams via the Prins-type cyclization of a carbamoyl chlo
Preparation of dihomoallylic secondary amines through samarium mediated allylation of oximes
Fan, Xuesen,Zhang, Yongmin
, p. 5475 - 5478 (2007/10/03)
The addition of allylsamarium bromide to oximes derived from aromatic aldehydes and methyl aryl ketones was studied and the dihomoallylic secondary amines were obtained in moderate to high yields under mild conditions.
Direct construction of quaternary carbon center utilizing an allylsamarium bromide reagent
Li, Zhifang,Zhang, Yongmin
, p. 5301 - 5306 (2007/10/03)
Direct geminal diallylation of lactones, lactams and acyclic amides containing a N-H bond has been achieved in the presence of allylsamarium bromide. By applying this method, quaternary carbons have been constructed, and 2,2-diallylated cyclic ethers, 2,2-diallylated nitrogen heterocycles and diallylated amides were synthesized in moderate to good yields under mild conditions.
Organoaluminum-Promoted Beckmann Rearrangement of Oxime Sulfonates
Maruoka, Keiji,Miyazaki, Tohru,Ando, Mamoru,Matsumura, Yasushi,Sakane, Soichi,et al.
, p. 2831 - 2843 (2007/10/02)
The Beckmann rearrangement of oxime sulfonates with simultaneous nucleophilic trapping of the intermediary iminocarbocation by organoaluminum reagents is described.This process provides a new and highly efficient route to imino thioethers, imino selenoethers, imino nitriles, and α-alkylated amines starting from oxime sulfonates by the use of dialkylaluminum thiolates, selenolates, diethylaluminum chloride-trimethylsilyl cyanide, and trialkylaluminum-diisobutylaluminum hydride systems, respectively.The present organoaluminum-promoted Beckmann rearrangement of oxime sulfonates has been successfully applied to the synthesis of naturally occuring alkaloids, pumiliotoxin C and solenopsin A and B, in stereoselective fashion.Moreover, α,α-dialkylation of amines can be realized by the successive treatment of oxime sulfonates with trialkylaluminum followed by allylic or propargylic Grignard reagents in synthetically useful yields.
