850352-11-3 Usage
Description
Pyrovalerone is a psychoactive compound with stimulatory effects. It is a controlled drug that has been found as a contaminant in products sold as bath salts. Naphyrone (hydrochloride) is an analog of pyrovalerone that is characterized by the substitution of the methylphenyl group of pyrovalerone with a naphthyl group. Naphyrone potently inhibits dopamine, serotonin, and norepinephrine transporters (IC50 = 20, 33, and 136 nM, respectively). Naphyrone, like pyrovalerone, has been detected in bath salt-type products. This compound is intended for forensic and research purposes.
Chemical Properties
Pale Yellow Solid
Uses
A Pyrovalerone (P997750) analog as selective dopamine transporter inhibitors.
Check Digit Verification of cas no
The CAS Registry Mumber 850352-11-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,0,3,5 and 2 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 850352-11:
(8*8)+(7*5)+(6*0)+(5*3)+(4*5)+(3*2)+(2*1)+(1*1)=143
143 % 10 = 3
So 850352-11-3 is a valid CAS Registry Number.
850352-11-3Relevant articles and documents
PYROVALERONE ANALOGS AND THERAPEUTIC USES THEREOF
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Page/Page column 32, (2008/06/13)
New compounds that bind to monoamine transporters are described. The compounds of the present invention can be racemic or pure R-or S-enantiomers. Certain preferred compounds of the present invention have a high selectively dopamine transporter versus the serotonin transporter. Preferred monoamine transporters for the practice of the present invention include the dopamine transporter, the serotonin transporter and the norepinephrine transporter.