850399-03-0

Basic information

• Product Name: Ethanone, 1-(3-chloro-2,4-dihydroxyphenyl)-
• CAS NO: 850399-03-0
• Molecular Formula: C8H7ClO3
• Molecular Weight: 186.595
• Mol File: 850399-03-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-(3-chloro-2,4-dihydroxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(3-chloro-2,4-dihydroxyphenyl)-(850399-03-0)
• EPA Substance Registry System: Ethanone, 1-(3-chloro-2,4-dihydroxyphenyl)-(850399-03-0)

Safety Data

• Hazardous Substances Data: 850399-03-0(Hazardous Substances Data)

Usage

Description

Ethanone, 1-(3-chloro-2,4-dihydroxyphenyl)-, is a versatile chemical compound characterized by an aromatic structure with a chloroand two hydroxy groups attached to a phenyl ring, along with a ketone functional group. Ethanone, 1-(3-chloro-2,4-dihydroxyphenyl)is known for its potential applications in the pharmaceutical industry due to its antibacterial and antifungal properties, as well as its ability to interact with enzymes and other biological molecules, making it a valuable building block for the creation of bioactive compounds.

Uses

Used in Pharmaceutical Industry:
Ethanone, 1-(3-chloro-2,4-dihydroxyphenyl)is used as an intermediate in the synthesis of various drugs and medications. Its unique structure and functional groups contribute to the development of new pharmaceutical compounds with improved therapeutic properties.
Used in Antimicrobial Agents:
Ethanone, 1-(3-chloro-2,4-dihydroxyphenyl)is used as an antimicrobial agent due to its inherent antibacterial and antifungal properties. Its potential use in the development of new antimicrobial agents can help address the growing issue of antibiotic resistance and the need for novel treatments against various infections.
Used in Bioactive Compounds:
The presence of hydroxy groups in Ethanone, 1-(3-chloro-2,4-dihydroxyphenyl)allows for interactions with enzymes and other biological molecules, making it a valuable building block for the creation of bioactive compounds. This property can be utilized in the design and synthesis of new compounds with specific biological activities, such as enzyme inhibitors, receptor agonists or antagonists, and other therapeutic agents.

Upstream product

• 89-84-9 2',4'-dihydroxy-4-acetophenone 

Relevant articles and documents

RadH: A Versatile Halogenase for Integration into Synthetic Pathways

Flavin-dependent halogenases are useful enzymes for providing halogenated molecules with improved biological activity, or intermediates for synthetic derivatization. We demonstrate how the fungal halogenase RadH can be used to regioselectively halogenate a range of bioactive aromatic scaffolds. Site-directed mutagenesis of RadH was used to identify catalytic residues and provide insight into the mechanism of fungal halogenases. A high-throughput fluorescence screen was also developed, which enabled a RadH mutant to be evolved with improved properties. Finally we demonstrate how biosynthetic genes from fungi, bacteria, and plants can be combined to encode a new pathway to generate a novel chlorinated coumarin “non-natural” product in E. coli.

2-OXO-5H-CHROMENO[4,3-B]PYRIDINES FOR USE IN THE TREATMENT OF HEPATITIS B

The present invention discloses compounds according to Formula (I), wherein R1, R2a, R2b, R3, R4, and R5 are as defined herein. The present invention relates to compounds, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of diseases involving hepatitis B by administering the compound of the invention.

Fibrinogen receptor antagonists and their use

This invention relates to novel fused bicyclic compounds of the general formula (I): wherein the symbols are defined herein, to pharmaceutical compositions containing the compounds, processes for preparing the compounds, and to methods of using the compounds, alone or in combination with other therapeutic agents. The compounds are antagonists of the platelet glycoprotein IIb/IIIa fibrinogen receptor complex, and are therefore useful for the inhibition of platelet aggregation, and for the treatment of thrombotic diseases and other diseases.