850448-72-5Relevant academic research and scientific papers
PYRIDOTHIOPHENE COMPOUNDS
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Page/Page column 16-17, (2008/06/13)
The use of compounds of formula (I) in therapy, particularly for the treatment of a disorder mediated by excessive or inappropriate HSP90 activity formula (I), wherein R2 is a group of formula (IA): -(Arl)m-(Alkl)p-(Z)r-(Alk2)S-Q (IA) Arl,Alk1, Z, Alk2 and Q being as defined in the specification; m, p, r and s are independently 0 or 1; R3 is hydrogen, an optional substituent, or an optionally substituted (Cl-C6)alkyl, aryl or heteroaryl radical; and R4 is a carboxylic ester, carboxamide or sulfonamide group; or a salt, N-oxide, hydrate, or solvate thereof.
