850467-19-5Relevant academic research and scientific papers
Structure-activity relationships of the cycloalkanol ethylamine scaffold: Discovery of selective norepinephrine reuptake inhibitors
Mahaney, Paige E.,Gavrin, Lori K.,Trybulski, Eugene J.,Stack, Gary P.,Vu, An T.,Cohn, Stephen T.,Ye, Fei,Belardi, Justin K.,Santilli, Arthur A.,Sabatucci, Joseph P.,Leiter, Jennifer,Johnston, Grace H.,Bray, Jenifer A.,Burroughs, Kevin D.,Cosmi, Scott A.,Leventhal, Liza,Koury, Elizabeth J.,Zhang, Yingru,Mugford, Cheryl A.,Ho, Douglas M.,Rosenzweig-Lipson, Sharon J.,Platt, Brian,Smith, Valerie A.,Deecher, Darlene C.
experimental part, p. 4038 - 4049 (2009/05/07)
Further exploration of the cycloalkanol ethylamine scaffold, of which venlafaxine (1) is a member, was undertaken to develop novel and selective norepinephrine reuptake inhibitors (NRIs) for evaluation in a variety of predictive animal models. These effor
