85048-32-4

Upstream product

• 13368-65-5 (3R)-3-methylcyclohexanone 
• 20628-90-4 2-Allyl-1,3-dimethyl-[1,3,2]diazaphospholidine 2-oxide 
• 146144-74-3 (3aS,7aS)-2-Allyl-1,3-dimethyl-octahydro-benzo[1,3,2]diazaphosphole 2-oxide 
• 85048-30-2 (Z,3R)-(-)-(3-methylcyclohexylidene)ethanol 
• 85048-26-6 (E,3R)-(-)-(3-methylcyclohexylidene)ethanol 
• 85114-21-2 (E,3R)-(-)-(3-methylcyclohexylidene)acetic acid 
• 85048-29-9 p-bromophenacyl (Z,3R)-(+)-(3-methylcyclohexylidene)acetate 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 85048-31-3 (Z,3R)-(-)-(3-methylcyclohexylidene)acetaldehyde 

Relevant academic research and scientific papers

EFFICIENT OLEFINATION WITH α-ALKYL CYCLIC PHOSPHONAMIDES

A variety of acyclic and cyclic aldehydes and ketones can be converted into the corresponding alkylidene, benzylidene and methoxycarbonyl alkylidene derivatives by treatment with 1,3,2-diazaphospholidine-2-alkyl-1,3-dimethyl 2-oxides (α-alkyl cyclic phosphonamides) under mild conditions.This olefination method is particularly useful in the case of enolizable carbonyl compounds.

STUDIES IN ASYMMETRIC OLEFINATIONS - THE SYNTHESIS OF ENANTIOMERICALLY PURE ALLYLIDENE, ALKYLIDENE, AND BENZYLIDENE CYCLOHEXANES

Treatment of alkyl cyclohexanones with topologically unique bicyclic phosphonamides derived from the C2 symmetrical (R,R)- and (S,S)-N,N'-dimethyl 1,2-trans-cyclohexane diamine leads to enantiomerically pure allylidene and benzylidene alkylcycl