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2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-amino-5-hydroxy-, monohydrochloride, also known as uracil, is a pyrimidine derivative with the molecular formula C4H5N3O3·HCl. It is an essential component of nucleic acids such as RNA and DNA, playing a vital role in the synthesis of nucleotides and nucleic acids for the storage and transmission of genetic information. Uracil is also utilized in the pharmaceutical industry as an intermediate for the production of various drugs, particularly anticancer and antiviral agents. Its diverse biological and industrial significance makes it a versatile compound.

85048-88-0

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85048-88-0 Usage

Uses

Used in Pharmaceutical Industry:
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-amino-5-hydroxy-, monohydrochloride is used as an intermediate in the production of various drugs for its role in the synthesis of nucleotides and nucleic acids, which are essential for the development of anticancer and antiviral agents.
Used in Medicine and Biochemistry:
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-amino-5-hydroxy-, monohydrochloride is used as a therapeutic agent for the treatment of certain diseases and disorders due to its potential applications in medicine and biochemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 85048-88-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,5,0,4 and 8 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 85048-88:
(7*8)+(6*5)+(5*0)+(4*4)+(3*8)+(2*8)+(1*8)=150
150 % 10 = 0
So 85048-88-0 is a valid CAS Registry Number.
InChI:InChI=1/C4H5N3O4/c5-4(11)1(8)6-3(10)7-2(4)9/h11H,5H2,(H2,6,7,8,9,10)

85048-88-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-amino-5-hydroxy-1,3-diazinane-2,4,6-trione,hydrochloride

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:85048-88-0 SDS

85048-88-0Downstream Products

85048-88-0Relevant academic research and scientific papers

Oxidation of Uric Acid. 4. Synthesis, Structure, and Diabetogenic Action of 5-Imino-2,4,6(1H,3H,5H)-pyrimidinetrione Salts and Their Alloxan-Like Covalent Adducts

Poje, Mirko,Rocic, Boris,Sikirica, Milan,Vickovic, Ivan,Bruvo, Milenko

, p. 861 - 864 (1983)

Three synthetic routes to salts of 5-amino-5-hydroxy-2,4,6(1H,3H,5H)-pyrimidinetrione (10) are described.The key reactions involved acid-catalyzed cleavage of 5-amino-5-ureido-2,4,6(1H,3H,5H)-pyrimidinetrione (7), conversion of uramil (8) to dehydrouramil (9) and subsequent hydration, and the condensation of alloxan (5) with ammonium salts.The carbinol ammonium salt structure 10a was unambiguously established by X-ray crystallography.New alloxan-like compounds 7, 9, and 10 were evaluated for diabetogenic activity in rats.Compound 7 was inactive, whereas compounds 9 and 10 showed the highest activity comparable to that of streptozotocin (12).

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