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Usage

Uses

Used in Pharmaceutical Industry:
5-BROMO-2-TERT-BUTOXY-PYRIDINE is used as a chemical intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapies. Its ability to participate in a range of chemical reactions makes it a crucial component in medicinal chemistry.
Used in Agrochemical Industry:
5-BROMO-2-TERT-BUTOXY-PYRIDINE is also used as an intermediate in the synthesis of agrochemicals, playing a significant role in the development of new pesticides and other agricultural products.
Used in Research and Development:
In the field of medicinal chemistry, 5-BROMO-2-TERT-BUTOXY-PYRIDINE is employed in research and development activities, aiding in the production of innovative drugs and therapies. Its versatility in chemical reactions is essential for exploring new chemical entities and potential applications.
It is important to handle 5-BROMO-2-TERT-BUTOXY-PYRIDINE with caution and adhere to proper safety protocols due to its potential health and environmental hazards.

Upstream product

• 624-28-2 2,5-dibromopyridine 
• 865-48-5 sodium t-butanolate 
• 865-47-4 potassium tert-butylate 

Downstream Products

• 948022-68-2 C₂₅H₂₉F₃N₂O₂ 
• 1300728-50-0 6-(tert-butoxy)-N-(2-chlorophenyl)pyridin-3-amine 
• 1421341-09-4 2-(tert-butoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 

Relevant academic research and scientific papers

Synthesis and evaluation of 2,5-linked alternating pyridine-thiophene oligomers

The first iterative access to alternating 2,5-linked pyridine-thiophene (Py-Th) oligomers is presented. These oligomers exhibit strong absorption and emission, even in the solid state (picture of the longest oligomer, above). Protonation leads to large red shifts in emission and, unlike most known thiophene-containing oligomers, they are readily reduced but not oxidized. These species represent a promising new class of materials for further study and potential application.

An improved Ullmann-Ukita-Buchwald-Li conditions for CuI-catalyzed coupling reaction of 2-pyridones with aryl halides

An effective CuI-trans-N,N′-dimethylcyclohexane-1,2-diamine (DMCDA)-K2CO3-catalyzed coupling reaction of 2-pyridones with aryl halides is described. Under our conditions, DMCDA was found to be an effective catalyst that facilitates the coupling reactions even in toluene, a common industrial solvent. In addition, 3-bromopyridine could also be coupled effectively under these conditions, indicating that the catalytic reactivity of this system is high. The reaction could be applied for polymer modification and iterative oligo-pyridone synthesis.