850543-71-4Relevant academic research and scientific papers
Diastereodivergent synthesis of 2,5-diketopiperazine derivatives of β-carboline and isoquinoline from L-amino acids
Siwicka, Aleksandra,Wojtasiewicz, Krystyna,Rosiek, Beata,Leniewski, Andrzej,Maurin, Jan K.,Czarnocki, Zbigniew
, p. 975 - 993 (2007/10/03)
Mild Pictet-Spengler-type condensation was applied to the synthesis of several tetrahydro-β-carboline and tetrahydro-isoquinoline derivatives. l-Amino acids were promoters of 1,4-chirality transfer with up to 100% de. The stereochemistry of the final dike
Diastereoselective synthesis of some β-carboline derivatives from L-amino acids
Siwicka, Aleksandra,Wojtasiewicz, Krystyna,Leniewski, Andrzej,Maurin, Jan K.,Czarnocki, Zbigniew
, p. 2295 - 2297 (2007/10/03)
L-Ala and L-Val were used as chiral inductors in a series of reactions in which a Pictet-Spengler cyclization, completed under mild conditions was the key step. Diketopiperazines 7a and 8a having R configuration at the newly created stereogenic center wer
