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1-Boc-6-methoxyindole-2-boronic acid is a chemical compound that features a boronic acid group attached to a 6-methoxyindole ring, with a tert-butoxycarbonyl (Boc) protecting group on the nitrogen atom of the indole ring. 1-Boc-6-methoxyindole-2-boronic acid is known for its role in organic synthesis and medicinal chemistry, serving as a versatile building block for the creation of biologically active molecules.

850568-65-9

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850568-65-9 Usage

Uses

Used in Organic Synthesis:
1-Boc-6-methoxyindole-2-boronic acid is used as a building block for the synthesis of various biologically active molecules, contributing to the development of new organic compounds with potential applications in various fields.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1-Boc-6-methoxyindole-2-boronic acid is utilized for the synthesis of pharmaceuticals, playing a crucial role in the discovery and development of new drugs with therapeutic potential.
Used in Pharmaceutical Development:
1-Boc-6-methoxyindole-2-boronic acid is employed as a key intermediate in the development of pharmaceuticals, facilitating the construction of complex molecular structures that can exhibit desired biological activities.
Used in Agrochemical Development:
1-Boc-6-methoxyindole-2-boronic acid is also used in the development of agrochemicals, where it serves as a building block for the synthesis of molecules with pesticidal or herbicidal properties, contributing to the advancement of crop protection strategies.
Used in Suzuki-Miyaura Cross-Coupling Reactions:
The boronic acid functionality in 1-Boc-6-methoxyindole-2-boronic acid makes it a valuable reagent for Suzuki-Miyaura cross-coupling reactions, a widely used method in organic chemistry for the formation of carbon-carbon bonds, enabling the synthesis of complex molecular structures with diverse applications.
Used in Other Organic Transformations:
Beyond Suzuki-Miyaura cross-coupling, 1-Boc-6-methoxyindole-2-boronic acid is also utilized in other types of organic transformations, further expanding its utility in the synthesis of a broad range of organic compounds.

Check Digit Verification of cas no

The CAS Registry Mumber 850568-65-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,0,5,6 and 8 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 850568-65:
(8*8)+(7*5)+(6*0)+(5*5)+(4*6)+(3*8)+(2*6)+(1*5)=189
189 % 10 = 9
So 850568-65-9 is a valid CAS Registry Number.
InChI:InChI=1/C14H18BNO5/c1-14(2,3)21-13(17)16-11-8-10(20-4)6-5-9(11)7-12(16)15(18)19/h5-8,18-19H,1-4H3

850568-65-9 Well-known Company Product Price

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  • Alfa Aesar

  • (H52482)  1-Boc-6-methoxyindole-2-boronic acid, 98%   

  • 850568-65-9

  • 250mg

  • 926.0CNY

  • Detail
  • Alfa Aesar

  • (H52482)  1-Boc-6-methoxyindole-2-boronic acid, 98%   

  • 850568-65-9

  • 1g

  • 2964.0CNY

  • Detail

850568-65-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (1-(tert-Butoxycarbonyl)-6-methoxy-1H-indol-2-yl)boronic acid

1.2 Other means of identification

Product number -
Other names [6-methoxy-1-[(2-methylpropan-2-yl)oxycarbonyl]indol-2-yl]boronic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:850568-65-9 SDS

850568-65-9Relevant academic research and scientific papers

Trisoxazoline/Cu(II)-catalyzed asymmetric intramolecular Friedel-Crafts alkylation reaction of indoles

Zhou, Jiao-Long,Ye, Meng-Chun,Sun, Xiu-Li,Tang, Yong

supporting information; experimental part, p. 6877 - 6881 (2009/12/06)

Intramolecular Friedel-Crafts alkylation reaction of indoles catalyzed by trisoxazoline/copper(II) is described. This annulation provides an easy access to polycyclic indole derivatives with up to 90% ee in up to 99% yield.

PYRIDINE AND PYRAZINE DERIVATIVES AS MNK KINASE INHIBITORS

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Page/Page column 149, (2008/06/13)

The present invention relates to compounds of the general formula (I) wherein X, Y, Z, A, Ar, R1, R2, R3, and R4 are as defined herein, which compounds are inhibitors of MNK2 and MNK1. The invention also relates to the use of the compounds in therapy, pharmaceutical compositions comprising the compounds, and the use of the compounds for the preparation of a medicament for the prophylaxis and treatment of disorders related to undesired activity of MNK1 and/or MNK2 kinases.

METHODS FOR TREATING HEPATITIS C

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Page/Page column 450, (2010/10/20)

In accordance with the present invention, compounds that inhibit viral replication, preferably Hepatitis C Virus (HCV) replication, have been identified, and methods for their use provided. In one aspect of the invention, compounds useful in the treatment

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