850582-85-3Relevant academic research and scientific papers
Preparation of 3-(fluoroalkyl)-2-azadienes and its application in the synthesis of (fluoroalkyl)isoquinoline and -pyridine derivatives
Palacios, Francisco,Alonso, Concepcion,Rodriguez, Marta,De Marigorta, Eduardo Martinez,Rubiales, Gloria
, p. 1795 - 1804 (2007/10/03)
A method for the preparation of 3-(fluoroalkyl)-substituted 2-azabutadienes 5 by aza-Wittig reaction of N-vinylic 3-(fluoro-alkyl)phosphazenes 4 and aldehydes is reported. Thermal 6π-electrocyclization of these azadienes gives 3-(fluoroalkyl)-substituted
Aza-Wittig reaction of fluoroalkylated N-vinylic phosphazenes with carbonyl compounds. Usefulness of 2-azadienes for the preparation of fluoroalkyl pyridine derivatives
Palacios, Francisco,Alonso, Concepción,Rubiales, Gloria,Villegas, Maite
, p. 2779 - 2794 (2007/10/03)
A method for the preparation of 3-fluoroalkyl substituted 2-aza-butadienes 6 by aza-Wittig reaction of 3-fluoroalkyl-N-vinylic phosphazenes 4 and aldehydes 5 is reported. [4+2] Cycloaddition reaction of these heterodienes 6 with enamines 9 gives fluoroalkyl substituted pyridine 15, 16, 24-27 and isoquinoline 12-14, 20 derivatives.
