850663-54-6 Usage
Description
4-Chloro-5-nitro-2-hydroxypyridine is an organic compound characterized by the presence of a chloro, nitro, and hydroxyl functional groups attached to a pyridine ring. It serves as a key intermediate in the synthesis of various chemical compounds and pharmaceuticals.
Uses
Used in Pharmaceutical Industry:
4-Chloro-5-nitro-2-hydroxypyridine is used as a reactant in the design and synthesis of a novel series of cyclohexyloxy-pyridyl derivatives. These derivatives act as inhibitors of diacylglycerol acyl transferase 1 (DGAT1), an enzyme involved in the regulation of lipid metabolism. By inhibiting DGAT1, these cyclohexyloxy-pyridyl derivatives have potential applications in the treatment of metabolic disorders and related health conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 850663-54-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,0,6,6 and 3 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 850663-54:
(8*8)+(7*5)+(6*0)+(5*6)+(4*6)+(3*3)+(2*5)+(1*4)=176
176 % 10 = 6
So 850663-54-6 is a valid CAS Registry Number.
InChI:InChI=1/C5H3ClN2O3/c6-3-1-5(9)7-2-4(3)8(10)11/h1-2H,(H,7,9)
850663-54-6Relevant articles and documents
NOVEL AROMATIC COMPOUND AND USE THEREOF
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, (2016/08/17)
Provided is a compound showing a bone formation promoting action (and/or bone resorption suppressive action). A compound of the formula (I) or a pharmacologically acceptable salt: [wherein each substituent is as defined in the DESCRIPTION], has low toxicity, shows good pharmacokinetics, has an action to promote bone formation, and is useful for the prophylaxis or To treatment of metabolic bone diseases (osteoporosis, fibrous osteitis (hyperparathyroidism), osteomalacia, Paget's disease that influences the systemic bone metabolism parameter etc.) associated with a decrease in the bone formation ability as compared to the bone resorption capacity.