850724-13-9

Basic information

• Product Name: 3-{4-[2-(decyl-pyridin-2-yl-amino)-ethoxy]-phenyl}-propionic acid methyl ester
• Synonyms: 3-{4-[2-(decyl-pyridin-2-yl-amino)-ethoxy]-phenyl}-propionic acid methyl ester
• CAS NO: 850724-13-9
• Molecular Weight: 440.626
• Mol File: 850724-13-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-{4-[2-(decyl-pyridin-2-yl-amino)-ethoxy]-phenyl}-propionic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-{4-[2-(decyl-pyridin-2-yl-amino)-ethoxy]-phenyl}-propionic acid methyl ester(850724-13-9)
• EPA Substance Registry System: 3-{4-[2-(decyl-pyridin-2-yl-amino)-ethoxy]-phenyl}-propionic acid methyl ester(850724-13-9)

Safety Data

• Hazardous Substances Data: 850724-13-9(Hazardous Substances Data)

Upstream product

• 101259-87-4 decyl-pyridine-2-yl-amine 
• 100388-13-4 methyl 3-(4-(2-bromoethoxy)phenyl)propanoate 
• 5597-50-2 3-(4-hydroxyphenyl)propionic acid methyl ester 
• 2016-57-1 1-aminodecane 
• 109-04-6 2-bromo-pyridine 

Relevant articles and documents

Design, synthesis, and biological activity of novel PPARγ ligands based on rosiglitazone and 15d-PGJ2

To develop novel PPARγ ligands, we synthesized thirteen 3-{4-(2-aminoethoxy)phenyl}propanoic acid derivatives, which are designed based on the structures of rosiglitazone and 15d-PGJ2. Among these compounds, compound 9 was found to be as potent as rosiglitazone in a binding assay and a preadipocyte differentiation test. Molecular modeling suggested that the nonyl group of 9 interacted with hydrophobic amino acid residues constructing the hydrophobic region of PPARγ protein where the alkyl chain of 15d-PGJ2 is expected to be located.