Cas 850787-01-8,4-(4-but-2-ynyloxy-benzenesulfonyl)-3-hydroxycarbamoyl-[1,4]diazepane-1-carboxylic acid <i>tert</i>-butyl ester

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Check Digit Verification of cas no

The CAS Registry Mumber 850787-01-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,0,7,8 and 7 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 850787-01:
(8*8)+(7*5)+(6*0)+(5*7)+(4*8)+(3*7)+(2*0)+(1*1)=188
188 % 10 = 8
So 850787-01-8 is a valid CAS Registry Number.

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850787-01-8Relevant academic research and scientific papers

Synthesis and SAR of diazepine and thiazepine TACE and MMP inhibitors

Zask, Arie,Kaplan, Joshua,Du, XueMei,MacEwan, Gloria,Sandanayaka, Vincent,Eudy, Nancy,Levin, Jeremy,Jin, Guixian,Xu, Jun,Cummons, Terri,Barone, Dauphine,Ayral-Kaloustian, Semiramis,Skotnicki, Jerauld

, p. 1641 - 1645 (2007/10/03)

Potent and selective TACE and MMP inhibitors utilizing the diazepine and thiazepine ring systems were synthesized and evaluated for biological activity in in vitro and in vivo models of TNF-α release. Oral activity in the mouse LPS model of TNF-α release

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