85083-91-6

Upstream product

• 73670-87-8 (E)-hexa-3,5-dien-1-ol 

Downstream Products

• 875303-25-6 [((E)-Hepta-4,6-diene)-1-sulfonyl]-benzene 
• 930269-86-6 (+/-)-methyl 2-(E)-phenylocta-5,7-dienoate 
• 1380544-76-2 (E)-methyl 1-(hexa-3,5-dienyl)cyclohexanecarboxylate 
• 1380544-49-9 (E)-5,5-diphenyl-2-(prop-1-enyl)tetrahydro-2H-pyran 
• 1380544-73-9 (E)-3,3-diphenylnona-6,8-dien-2-ol 
• 1380544-81-9 C₂₀H₂₀O 
• 1380544-65-9 (E)-(1-(hexa-3,5-dienyl)cyclohexyl)methanol 
• 1380544-64-8 (E)-2,2-diphenylocta-5,7-dien-1-ol 
• 1351511-28-8 (E)-N-(2,2-dimethylocta-5,7-dien-1-yl)-4-methoxybenzenesulfonamide 
• 136429-52-2 nona-6t,8-dien-2-one 
• 89116-40-5 Toluene-4-sulfonic acid 3-((E)-hexa-3,5-dienyl)-4,4-dimethyl-2-oxo-cyclopentylmethyl ester 

Relevant academic research and scientific papers

Tandem intramolecular Diels-Alder (TIMDA) reactions: Branched substrate studies and new synthetic pathways

Using a malonic ester route, the first branched tandem intramolecular Diels-Alder (TIMDA) precursor, 3, was synthesized from sorbic acid in seven steps (15% overall yield). Treatment with Lewis acid catalysts (e.g., boron trifluoride etherate) affects the TIMDA reaction to afford a new fused-tetracyclic, 4, as two diastereomers (1:1). An alternative synthetic route to key intermediates used in the synthesis of linear TIMDA precursors has also been achieved.