850833-52-2Relevant academic research and scientific papers
Stereocontrolled synthesis of all eight stereoisomers of the putative anti-androgen cyoctol
Mulzer, Johann,Kaselow, Ulrich,Graske, Klaus-Dieter,Kühne, Holger,Sieg, Andreas,Martin, Harry J.
, p. 9599 - 9614 (2007/10/03)
All eight stereoisomers (1-4 and enantiomers) of the putative anti-androgen cyoctol have been synthesized along stereochemically unambiguous routes. The biological tests of all isomers indicated that cyoctol is not an anti-androgen, contrary to the patent literature. All eight stereoisomers of the putative anti-androgen cyoctol have been prepared and tested biologically.
