850877-60-0

Usage

Uses

Used in Pharmaceutical Research:
2-BOC-5-ACETYL-ISOINDOLINE is used as a building block for the synthesis of various pharmaceuticals and fine chemicals. Its unique structure and functional groups make it a versatile component in the creation of new drug candidates, contributing to the advancement of medicinal chemistry.
Used in Organic Synthesis:
In the field of organic synthesis, 2-BOC-5-ACETYL-ISOINDOLINE is employed as a key intermediate. Its presence allows for the construction of complex organic molecules, facilitating the development of novel chemical entities with potential applications in various industries.
Used in Medicinal Chemistry Research:
2-BOC-5-ACETYL-ISOINDOLINE serves as a valuable tool in medicinal chemistry research. Its ability to be modified and incorporated into diverse chemical structures makes it instrumental in the exploration of new therapeutic agents and the understanding of molecular interactions within biological systems.

Upstream product

• 201940-08-1 5-bromo-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester 
• 97674-02-7 tributyl(1-ethoxyvinyl)stannane 
• 1056156-64-9 C₁₇H₂₃NO₃ 

Downstream Products

• 850877-61-1 C₁₅H₁₈BrNO₃ 
• 850877-62-2 C₁₉H₂₅N₃O₂S 
• 905274-46-6 1-(isoindolin-5-yl)ethan-1-one 

Relevant academic research and scientific papers

ADAMTS INHIBITORS, PREPARATION METHODS AND MEDICINAL USES THEREOF

Compounds of formula (I) useful as inhibitors of ADAMTS-5 and/or ADAMTS-4, pharmaceutical compositions thereof, and use of them as therapeutic agents for the treatment of diseases involving degradation of cartilage or disruption of cartilage homeostasis, in particular osteoarthrosis and/or rheumatoid arthritis, are disclosed.

HETERO-HALO INHIBITORS OF HISTONE DEACETYLASE

This invention provides compounds that are inhibitors of HDAC2. The compounds (e.g., compounds according to Formula I, II or any of Compounds 100-128 or any of those in Tables 2 or 3) accordingly are useful for treating, alleviating, or preventing a condition in a subject such as a neurological disorder, memory or cognitive function disorder or impairment, extinction learning disorder, fungal disease or infection, inflammatory disease, hematological disease, or neoplastic disease, or for improving memory or treating, alleviating, or preventing memory loss or impairment.

MACROCYCLIC CARBOXYLIC ACIDS AND ACYLSULFONAMIDES AS INHIBITORS OF HCV REPLICATION

The present invention provides compounds of the general formulas I-IX, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The present invention further provides treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.