85092-82-6

Usage

Uses

Used in Pharmaceutical Industry:
1H-Indole, 3-Bromo-5-Chlorois used as a chemical intermediate for the synthesis of various pharmaceuticals, including anti-inflammatory drugs, antimicrobial agents, and anticancer medications. Its unique structure and properties contribute to the development of effective therapeutic agents.
Used in Agrochemical Industry:
1H-Indole, 3-Bromo-5-Chlorois utilized in the production of agrochemicals for plant protection. It serves as a key component in the formulation of pesticides and other agrochemical products, helping to protect crops from pests and diseases.
Used in Material Science:
1H-Indole, 3-Bromo-5-Chlorohas potential applications in the field of material science, particularly in the development of new materials with specific properties and functionalities. Its unique structure and properties can be harnessed to create innovative materials for various applications.
Safety Precautions:
As with any chemical compound, proper handling and safety precautions are crucial when working with 1H-Indole, 3-Bromo-5-Chloro-. It is essential to follow established safety guidelines and protocols to prevent potential hazards and ensure safe usage.

InChI:InChI=1/C8H5BrClN/c9-7-4-11-8-2-1-5(10)3-6(7)8/h1-4,11H

Upstream product

• 17422-32-1 5-chloro-1H-indole 

Downstream Products

• 22072-89-5 5-Chloro-3-phenyl-1H-indole 

Relevant academic research and scientific papers

Preparation method of 5-bromo-2-chloro-7H-pyrrolo [2, 3-d] pyrimidine

The invention discloses a preparation method of 5-bromo-2-chloro-7H-pyrrolo[2, 3-b] pyridine. According to the method, 2,4-chloro-7H-pyrrolo[2, 3-d] pyrimidine is used as a starting raw material, in the presence of zinc powder and acetic acid, selective d

PhI(OAc)2/NaX-mediated halogenation providing access to valuable synthons 3-haloindole derivatives

This paper describes a mild phenyliodine diacetate mediated method for selective chlorination, bromination, and iodination of indole C-H bonds using sodium halide as a source for analogous halogenations. The combination of NaX and phenyliodine diacetate provides an invincible system for halogenation of indoles. This protocol was compatible with a wide array of indole substrates and provides straight forward access to potential halogenated arenes.

Synthesis and biological activities of isogranulatimide analogues

The synthesis of new isogranulatimide analogues, their inhibitory activities toward the Checkpoint 1 kinase (Chk1), and their in vitro cytotoxicities toward four tumor cell lines (one murine L1210 leukemia, and three human cell lines: DU145 prostate carci

Synthesis of isogranulatimide analogues possessing a pyrrole moiety instead of an imidazole heterocycle

An efficient four step synthesis from commercial indoles of isogranulatimide analogues is reported. In the new compounds, the imidazole moiety is replaced by a pyrrole unit, the indole part is substituted or not in 5-position and the nitrogen of the imide moiety bears or not a methyl substituent.