85099-96-3

Upstream product

• 85099-94-1 (2R,3S)-1-Benzyloxy-3-methyl-hexan-2-ol 
• 110918-65-5 (2'S,3'R)-2',3'-epoxyhexyl 3,5-dinitrobenzoate 
• 75-24-1 trimethylaluminum 
• 106498-75-3 2,3-epoxyhexanol 
• 98-59-9 p-toluenesulfonyl chloride 
• 76741-13-4 (2R,3S)-3-methylhexane-1,2-diol 
• 94992-76-4 (2S,3R)-2,3-epoxy-1-hexanol 

Downstream Products

• 110918-75-7 (2R,3R,4S)-2,4-dimethyl-3-tetrahydropyranyloxyheptyl tosylate 

Relevant academic research and scientific papers

SYNTHESIS OF BOTH THE ENANTIOMERS OF INVICTOLIDE, A PHEROMONE COMPONENT OF THE RED IMPORTED FIRE ANT

Both the enantiomers of invictolide were synthesized in 17 steps from propargyl alcohol.

Synthesis of (3S,4S)-4-Methyl-3-heptanol and Its (3S,4R)-Isomer Employing Asymmetric Epoxidation Coupled with Regioselective Cleavage of Epoxides with Trimethylaluminum

(3S,4S)-(-)-4-Methyl-3-heptanol, the key compound in the aggregation pheromone of Scolytus multistriatus Marsham, was synthesized by employing asymmetric epoxidation and epoxide cleavage with trimethylaluminum as the key steps. (3S,4R)-(+)-4-Methyl-3-heptanol was also synthesized.

SYNTHESIS OF THE ENANTIOMERIC FORMS OF CIS AND TRANS 1-BENZYLOXY-2,3-EPOXY BUTANE AND OF (3S,4S) 4-METHYL-3-HEPTANOL

The C4 erythro and threo diols (7) and (8) are converted either into the chiral epoxides (13) and (15) or into the enantiomers (14) and (16); the epoxide (13) is used as chiral synthon for the preparation of (3S,4S) 4-methyl-3-heptanol (21).