851033-73-3Relevant academic research and scientific papers
Using biological performance similarity to inform disaccharide library design
Tanikawa, Tetsuya,Fridman, Micha,Zhu, Wenjiang,Faulk, Brian,Joseph, Isaac C.,et al.
supporting information; experimental part, p. 5075 - 5083 (2009/09/30)
Designing better small-molecule discovery libraries requires having methods to assess the consequences of different synthesis decisions on the biological performance of resulting library members. Since we are particularly interested in how stereochemistry
Synthesis and evaluation of mimetics of UDP and UDP-α-D-galactose, dTDP and dTDP-α-D-glucose with monosaccharides replacing the key pyrophosphate unit
Ballell, Lluis,Young, Robert J.,Field, Robert A.
, p. 1109 - 1115 (2007/10/03)
A series of 5′-O-glycosyl-uridine and thymidine derivatives have been prepared as potential mimics of sugar nucelotides and nucleotide-diphosphates. These compounds proved not to be inhibitors of bovine β-1,4- galactosyltransferase although some showed mo
