851069-90-4

Upstream product

• 851069-89-1 3-chloromethyl-2-methyl-6-(4-trifluoromethyl-phenyl)-pyridine 
• 143-33-9 sodium cyanide 

Downstream Products

• 851069-91-5 [2-methyl-6-(4-trifluoromethyl-phenyl)-pyridin-3-yl]-acetic acid 

Relevant academic research and scientific papers

Benzannelated derivatives, their manufacture and use as pharmaceutical agents

There are presented compounds of the formula wherein R6 and R7 is R4 and R5 or R5 and R6 together with the carbon atoms to which they are attached, form a ring as defined in the description

Phenyl derivatives, their manufacture and use as pharmaceutical agents

This invention relates to compounds of the formula wherein one of R5, R6 and R7 is and X1, X2, Y1 to Y4, R1 to R13 and m and n are defined in the description, and to all enantiomers and pharmaceutically acceptable salts and/or esters thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are modulated by PPARδ and/or PPARα agonists.

Indolyl and dihydroindolyl derivatives, their manufacture and use as pharmaceutical agents

This invention relates to compounds of the formula wherein one of R6, R7 and R8 is and X, Y1 to Y4, R1 to R14 and n are as defined in the description, and to all enantiomers and pharmaceutically acceptable salts and/or esters thereof The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are modulated by PPARδ and/or PPARα agonists.