85107-55-7

Usage

Uses

suzuki reaction

InChI:InChI=1/C8H8BNO6/c1-16-8(11)5-2-3-6(9(12)13)7(4-5)10(14)15/h2-4,12-13H,1H3

Upstream product

• 106-38-7 para-bromotoluene 
• 5720-05-8 4-methylphenylboronic acid 
• 14047-29-1 4-carboxyphenylboronic acid 
• 89976-27-2 methyl ester of 4-iodo-3-nitrobenzoic acid 

Downstream Products

• 100958-97-2 4-methoxycarbonyl-2-nitro-phenylmercury ⁽¹⁺⁾; chloride 
• 380430-55-7 (2-amino-4-(methoxycarbonyl)phenyl)boronic acid hydrochloride salt 
• 618-95-1 methyl 3-nitrobenzoate 
• 65235-35-0 dimethyl 2,2’-dinitro-[1,1’-biphenyl]-4,4’-dicarboxylate 

Relevant academic research and scientific papers

Promoting reductive tandem reactions of nitrostyrenes with Mo(CO)6 and a palladium catalyst to produce 3 h -indoles

The combination of Mo(CO)6 and 10 mol % of palladium acetate catalyzes the transformation of 2-nitroarenes to 3H-indoles through a tandem cyclization-[1,2] shift reaction of in situ generated nitrosoarenes. Mo(CO)6 appears to have dual roles in this transformation: generate CO and promote C-N bond formation to increase the yield of the N-heterocycle product.

Synthesis of 2-amino-4-(methoxycarbonyl)phenylboronic acid hydrochloride, a key intermediate for the synthesis of quinolines derivatives

A practical and efficient process for the synthesis in good yield of 2-amino-4-(methoxycarbonyl)phenylboronic acid hydrochloride from p-bromo toluene has been developed via borylation, oxidation, nitration, esterification and hydrogenation.